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CUREX PTCA Dilatation Balloon Catheter

The CUREX Paclitaxel Drug Eluting Rapid Exchange PTCA (Percutaneous Transluminal Coronary Angioplasty) balloon catheter is a drug-releasing balloon system for the treatment of coronary vessels. CUREX is designed to improve the lumen diameter and to reduce restenosis in the treatment of lesions in native coronary arteries.

CUREX- A Novel Concept…

The balloon section of the distal end of the catheter is coated with formulation of Paclitaxel drug and binding agent. When in contact with the body fluid the hydrophilic binding agent swells and open the structure for the pressure induced fast release of paclitaxel drug into the vessel wall.

Intended Use

CUREX Paclitaxel Drug Eluting PTCA balloon Catheter is intended for treatment of atherosclerotic depositions in coronary lesions, specifically in patients with either in-stent restenosis or de novo coronary lesions with a reference vessel diameter ranging from 2.00mm to 4.50mm and lesion lengths up to 40mm and it is also intended for pre and post dilatation during coronary stent implantation for improving luminal diameter.

Paclitaxel Drug: A Proven anti-proliferative drug

Paclitaxel drug is a proven anti-proliferative drug that blocks cellular proliferation and migration. The CUREX is a coated with a safe and uniform dose of Paclitaxel for consistent vessel treatment.

Why Paclitaxel for DEB??

Paclitaxel was identified as the primary drug for DEB because:

Highly lipophilic hence binds to tissue at the target site and resists wash-out
Antiproliferative drug.
Safe and Reliable quantitative Drug deposition into the vessel wall

Unique Design Features of CUREX

It is Effective
Lower restenosis rates than standard PTCA/PTA treatments
Fast recovery of endothelial function
Potential decrease in anti-platelet therapy
Potential for homogenous drug delivery to the vessel wall, unlike DES
Minimal Drug loss during inflation
Safe and Reliable quantitative Drug deposition into the vessel wall
Homogenous drug distribution

Technical Specification of CUREX PTCA

Specifications of CUREX Paclitaxel Drug Eluting PTCA Dilatation Balloon Catheter
Available Balloon lengths (mm)	9, 14, 17, 20, 25, 30, 33, 38 & 41
Available Vessel Diameters (mm)	2.00 to 4.50
Drug	Paclitaxel
Drug Dose	2.3 µg/mm2
Balloon Material	Polyamide
Catheter Design	Rapid Exchange delivery system
Usable Shaft Length (cm)	140
Guidewire Compatibility	0.014”
Guiding Catheter Inner Diameter	5 Fr (0.056”) (1.4 mm) Compatible
Catheter Outer Shaft Diameter	2.70 Fr Proximally, 1.95 Fr Distally
Hydrophilic Coating	On the distal and proximal shaft of balloon delivery system
Balloon Inflation Pressure	Nominal Pressure (NP): 8 atm Rated Burst Pressure (RBP): 16 atm (for: Balloon Diameter 2.00 to 4.00mm) 14 atm (for: Balloon Diameter 4.50)